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Catalog Number | orb1986478 |
---|---|
Category | Small Molecules |
Description | BAY-850 HCl |
MW | 800.08 |
SMILES | O=C(N[C@H](CC1=CC=C(C#N)C=C1)CNC2CCC(N)CC2)C3=CC(C4=CC=C(CN[C@@H](C5=CC=C(C)C=C5)C)O4)=C(OC)C=C3Cl.[H]Cl.[H]Cl.[H]Cl.[H]Cl |
Formula | C38H48Cl5N5O3 |
Biological Activity | BAY-850 is a chemical probe for the bromine domain of Atad2A. It replaces acetylated H4 peptides from the bromine domain of Atad2. AY-850 shows superior selectivity to all other bromine domains (not hit in 10 μm Bromoscan). Full-length ATAD2 was replaced from chromatin in living cells at a concentration of 1 μm determined by FRAP. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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