BAFF Recombinant Protein

• Catalog Number: orb1230110
• Category: Proteins
• Description: BAFF Recombinant Protein
• Tag: Fc Tag
• Concentration: 0.1mg/ml after reconstitution.
• Dilution range: This recombinant proteins is for research use only.
• Form/Appearance: Lyophilized
• Purity: > 95% (SDS-PAGE). Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
• Target: TNFSF13B
• UniProt ID: P25311
• Protein Sequence: The receptor-binding domain of human BAFF (aa 136-285) is fused at the N-terminus to the Fc portion of human IgG1.
• Source: CHO cells
• Biological Activity: Rescues the production of mature follicular and marginal zone B cells. - in vitro: Addition of 1-100 ng/ml of Fc-BAFF induces B cell survival in a dose-dependent manner. - in vivo: Fc-BAFF treatment rescues mature B cell development in BAFF deficient mice. Mice are injected at day 0 with 100 ug Fc-BAFF i.v. and at day 14 with 50 ug Fc-BAFF i.p.
• NCBI: Q9Y275
• Storage: Stable for at least 6 months after receipt when stored at -20°C.
• Buffer/Preservatives: Contains PBS. Reconstitute with 100 μl sterile water.
• Alternative names: BLyS, TALL-1, CD257, B Cell Activating Factor, TNF
• Note: For research use only
• Application notes: This recombinant proteins is for research use only.
• Expiration Date: 6 months from date of receipt.