Azido-PEG4-Val-Cit-PAB-MMAE

• Catalog Number: orb1984689
• Category: Small Molecules
• Description: Azido-PEG4-Val-Cit-PAB-MMAE
• CAS Number: 1869126-64-6
• MW: 1396.737
• SMILES: [H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCN=[N+]=[N-])C(C)C)cc1)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1 |@:79|
• Formula: C₆₉H₁₁₃N₁₃O₁₇
• Biological Activity: Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Azido-PEG4-Val-Cit-PAB-OH.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.