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Catalog Number | orb757582 |
---|---|
Category | Small Molecules |
Description | AZD5718 (AZD-5718, AZD 5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM; exhibits LTB4 inhibition in human whole blood assays with IC50 of 39 nM; reduce the production of pro-inflammatory and vasoactive leukotrienes both in vitro and in vivo. |
CAS Number | [2041075-86-7] |
MW | 446.511 |
SMILES | O=C([C@H]1[C@H](C(C2=CC=C(C3=NNC(C)=C3)C=C2)=O)CCCC1)NC4=C(N(N=C4)CCN5)C5=O |
Formula | C24H26N6O3 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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