AZD5718

• Catalog Number: orb1739510
• Category: Small Molecules
• Description: AZD5718
• CAS Number: 2041076-43-9
• Purity: 0.98
• MW: 530.62
• SMILES: CC=1C=C(N(N1)C2CCCCO2)C3=CC=C(C(=O)[C@H]4[C@H](C(NC5=C6N(N=C5)CCNC6=O)=O)CCCC4)C=C3
• Formula: C₂₉H₃₄N₆O₄
• Biological Activity: AZD5718 is a potent and selective FLAP inhibitor (IC50 = 2.0 nM) for Treatment of Coronary Artery Disease. AZD5718 demonstrated a dose dependent and greater than 90% suppression of leukotriene production over 24 h. Preclinical toxicology studies in rat and dog did not show any serious adverse events of clinical significance. Currently, AZD5718 is evaluated in a phase 2a study for treatment of coronary artery disease.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.