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Catalog Number | orb1707611 |
---|---|
Category | Small Molecules |
Description | AZD2906 |
CAS Number | 1034148-15-6 |
MW | 460.5 |
SMILES | O([C@@H]([C@@H](NC(=O)C1CC1)C)C=2C=CC(OC)=NC2)C=3C=C4C(N(N=C4)C5=CC=C(F)C=C5)=CC3 |
Formula | C26H25FN4O3 |
Biological Activity | AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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