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Catalog Number | orb146240 |
---|---|
Category | Small Molecules |
Description | AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows > 14-fold selectivity against CDK2, CDK5, CDK1 and Erk2. |
CAS Number | [612487-72-6] |
MW | 334.3718 |
SMILES | O1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C(C([H])=C2[H])C2=C(N([H])C3C([H])=C([H])C(C#N)=C([H])C2=3)O[H])C([H])([H])C1([H])[H] |
Formula | C19H18N4O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of AZD1080