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Catalog Number | orb1302029 |
---|---|
Category | Small Molecules |
Description | AZ304 |
CAS Number | 942507-42-8 |
Purity | 99.83% |
MW | 451.52 |
SMILES | COc1ccc2c(Nc3cc(NC(=O)c4cccc(c4)C(C)(C)C#N)ccc3C)ncnc2c1 |
Formula | C27H25N5O2 |
Biological Activity | AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |