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Catalog Number | orb1300875 |
---|---|
Category | Small Molecules |
Description | AZ 628 |
CAS Number | 878739-06-1 |
Purity | 98.54% |
MW | 451.52 |
SMILES | O=C1C=2C(=CC=C(NC3=CC(NC(=O)C4=CC(C(C#N)(C)C)=CC=C4)=CC=C3C)C2)N=CN1C |
Formula | C27H25N5O2 |
Biological Activity | AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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