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Catalog Number | orb134829 |
---|---|
Category | Small Molecules |
Description | Axitinib is a non-selective receptor kinase inhibitor of Flt and Flk proteins. This compound also inhibits VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-β and c-KIT with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively. Axitinib is studied as an ant |
CAS Number | [319460-85-0] |
MW | 386.469522953033 |
SMILES | CNC(C1C=CC=CC=1SC1=CC=C2C(=NNC2=C1)C=CC1C=CC=CN=1)=O |
Formula | C22H18N4OS |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of Axitinib