Axitinib

• Catalog Number: orb1308579
• Category: Small Molecules
• Description: Axitinib
• CAS Number: 319460-85-0
• Purity: 99.53%
• MW: 386.47
• SMILES: C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2
• Formula: C₂₂H₁₈N₄OS
• Biological Activity: Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.