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Catalog Number | orb1740592 |
---|---|
Category | Small Molecules |
Description | Avatrombopag maleate |
CAS Number | 677007-74-8 |
Purity | 0.98 |
MW | 765.72 |
SMILES | OC(=O)\C=C/C(O)=O.OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(-c2cc(Cl)cs2)c(s1)N1CCN(CC1)C1CCCCC1 |
Formula | C33H38Cl2N6O7S2 |
Biological Activity | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 may be useful in the treatment of patients with thrombocytopenia. Avatrombopag was first approved in 2018. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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