Avasimibe

• Catalog Number: orb1305068
• Category: Small Molecules
• Description: Avasimibe
• CAS Number: 166518-60-1
• Purity: 98.77%
• MW: 501.72
• SMILES: CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C
• Formula: C₂₉H₄₃NO₄S
• Biological Activity: Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 μM).
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.