AV-412

• Catalog Number: orb1309962
• Category: Small Molecules
• Description: AV-412
• CAS Number: 451493-31-5
• Purity: 99.85%
• MW: 851.41
• SMILES: Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C
• Formula: C₄₁H₄₄ClFN₆O₇S₂
• Biological Activity: AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.