AV-412 free base

• Catalog Number: orb1678998
• Category: Small Molecules
• Description: AV-412 free base
• CAS Number: 451492-95-8
• MW: 507
• SMILES: N(C=1C2=C(C=C(C#CC(C)(C)N3CCN(C)CC3)C(NC(C=C)=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
• Formula: C₂₇H₂₈ClFN₆O
• Biological Activity: AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.