ATM Inhibitor-1

• Catalog Number: orb1710372
• Category: Small Molecules
• Description: ATM Inhibitor-1
• CAS Number: 2135639-94-8
• Purity: 98%
• MW: 492.61
• SMILES: N([C@@H](C)C1CCOCC1)C=2C3=C(N=NC2C(NC)=O)C=CC(=C3)C=4C=CC(OCCCN(C)C)=NC4
• Formula: C₂₇H₃₆N₆O₃
• Biological Activity: ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM).
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.