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Catalog Number | orb1981729 |
---|---|
Category | Tools |
Description | ATI-2341 TFA |
MW | 2370.84 |
Formula | C106H179F3N26O27S2 |
Biological Activity | ATI-2341 is a potent, functionally selective allosteric agonist of the C-X-C chemokine receptor type 4 (CXCR4), acting as a biased ligand that prefers Gαi activation over Gα13. This compound activates the inhibitory heterotrimeric G protein (Gi), leading to reduced cAMP production and enhanced calcium mobilization. ATI-2341 effectively mobilizes bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) [1] [2]. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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