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Catalog Number | orb1705008 |
---|---|
Category | Small Molecules |
Description | AT7867 dihydrochloride |
CAS Number | 1431697-86-7 |
MW | 410.77 |
SMILES | C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl.Cl.Cl |
Formula | C20H22Cl3N3 |
Biological Activity | AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA kinase with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. AT7867 dihydrochloride is able to induce pharmacodynamic changes and inhibit human tumor xenograft growth. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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