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Catalog Number | orb1309989 |
---|---|
Category | Small Molecules |
Description | APX-115 free base |
CAS Number | 1270084-92-8 |
Purity | 99.03% |
MW | 279.34 |
SMILES | C(CC)C=1C(=NN(C1O)C2=CC=CC=N2)C3=CC=CC=C3 |
Formula | C17H17N3O |
Biological Activity | APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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