Apricitabine

• Catalog Number: orb1707644
• Category: Small Molecules
• Description: Apricitabine
• CAS Number: 160707-69-7
• Purity: 98%
• MW: 229.26
• SMILES: O=C1N([C@@]2(S[C@H](CO)OC2)[H])C=CC(N)=N1
• Formula: C₈H₁₁N₃O₃S
• Biological Activity: Apricitabine (SPD754; AVX754) shows promising antiretroviral efficacy, good tolerability and a low propensity for resistance selection in antiretroviral-naive HIV infection[2]. Apricitabine (SPD754; AVX754), the (-) enantiomer of 2′-deoxy-3′-oxa-4′-thiocytidine (dOTC), is a highly selective and orally active HIV-1 reverse transcriptase (RT) inhibitor (Ki=0.08 μM). It also inhibits DNA polymerases α, β, and γ with Ki value of 300 μM, 12 μM, and 112.25 μM, respectively[1].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.