APJ receptor agonist 5

• Catalog Number: orb1686887
• Category: Small Molecules
• Description: APJ receptor agonist 5
• CAS Number: 2135514-20-2
• Purity: 98%
• MW: 479.52
• SMILES: C(OCC)C=1N(C(O)=C(C(=O)N2C[C@H](CC2)C3=CC=CC=C3)C(=O)N1)C4=C(OC)C=CC=C4OC
• Formula: C₂₆H₂₉N₃O₆
• Biological Activity: APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor ( APJ ) with an EC 50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease [1].
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.