APJ receptor agonist 1

• Catalog Number: orb1691035
• Category: Small Molecules
• Description: APJ receptor agonist 1
• CAS Number: 2287153-38-0
• Purity: 98%
• MW: 524.02
• SMILES: CCCC(NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1
• Formula: C₃₁H₂₆ClN₃O₃
• Biological Activity: APJ receptor agonist 1, a potent biphenyl acid derivative, acts as an agonist (EC50 of 0.093 nM and 0.12 nM for human and rat APJ receptors, respectively) for the APJ receptor (APJ-R). It exhibits significant in vitro potency towards apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 holds promise for heart failure research.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.