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Catalog Number | orb1691035 |
---|---|
Category | Small Molecules |
Description | APJ receptor agonist 1 |
CAS Number | 2287153-38-0 |
Purity | 98% |
MW | 524.02 |
SMILES | CCCC(NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |
Formula | C31H26ClN3O3 |
Biological Activity | APJ receptor agonist 1, a potent biphenyl acid derivative, acts as an agonist (EC50 of 0.093 nM and 0.12 nM for human and rat APJ receptors, respectively) for the APJ receptor (APJ-R). It exhibits significant in vitro potency towards apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 holds promise for heart failure research. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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