Apitolisib

• Catalog Number: orb154688
• Category: Small Molecules
• Description: GDC-0980 (RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM, respectively. Also a mTOR inhibitor with Ki of 17 nM, and highly selective versus others PIKK family kinases.
• CAS Number: [1032754-93-0]
• MW: 498.6011
• SMILES: C[C@H](O)C(N1CCN(CC2=C(C)C3=NC(C4=CN=C(N)N=C4)=NC(N5CCOCC5)=C3S2)CC1)=O
• Formula: C₂₃H₃₀N₈O₃S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.