Apitolisib

• Catalog Number: orb1307117
• Category: Small Molecules
• Description: Apitolisib
• CAS Number: 1032754-93-0
• Purity: 99.52%
• MW: 498.6
• SMILES: CC=1C=2C(=C(N=C(N2)C=3C=NC(N)=NC3)N4CCOCC4)SC1CN5CCN(C([C@H](C)O)=O)CC5
• Formula: C₂₃H₃₀N₈O₃S
• Biological Activity: Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα(IC50=5 nM), PI3Kβ(IC50=27 nM), PI3Kδ(IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, among others.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.