AP1189 acetate

• Catalog Number: orb2279766
• Category: Small Molecules
• Description: AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ～3-fold.
• CAS Number: [959850-74-9]
• MW: 358.35
• SMILES: N1(C2C=CC=CC=2[N+]([O-])=O)C(=CC=C1)/C=C/C=N/NC(N)=N.OC(=O)C
• Formula: C₁₆H₁₈N₆O₄
• Note: For research use only
• Expiration Date: 12 months from date of receipt.