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Catalog Number | orb2279766 |
---|---|
Category | Small Molecules |
Description | AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ~3-fold. |
CAS Number | [959850-74-9] |
MW | 358.35 |
SMILES | N1(C2C=CC=CC=2[N+]([O-])=O)C(=CC=C1)/C=C/C=N/NC(N)=N.OC(=O)C |
Formula | C16H18N6O4 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.73% | |
959850-74-9 | |
358.35 | |
C16H18N6O4 |
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