Antibiofilm agent-12

SKU: orb2664856

Description

Antibiofilm agent-12 (Compound C13), an antifungal belonging to the carbamate derivatives, exhibits significant antifungal activity against Candida auris, with an MIC90 of 237.9 μM. It inhibits the drug efflux pump activity of Candida auris and promotes ergosterol depletion, thereby hindering the formation of Candida auris biofilms and reducing its metabolic flexibility. Additionally, Antibiofilm agent-12 demonstrates antifungal efficacy in a C. elegans model following Candida auris infection.

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Key Properties

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CAS Number	480452-24-2
MW	262.69
Formula	C₁₃H₁₁ClN₂O₂
SMILES	O=C(OC=1C=CC=CC1)NNC2=CC=C(Cl)C=C2

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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