Anti-ROR1 Reference Antibody

• Catalog Number: orb1805459
• Category: Antibodies
• Description: Anti-ROR1 Reference Antibodyd antibody and Monomethyl auristatin E (MMAE) used for the study of several solid tumors.
• Clonality: Monoclonal
• Tested applications: ELISA, FA, FACS, Kinetics
• Reactivity: Human
• Isotype: IgG
• Purity: > 95%
• Conjugation: Unconjugated
• MW: 146.14 kDa
• Target: ROR1
• Endotoxins: < 1 EU/mg
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 100 mM Pro-Ac 20 mM Arg pH 5.0
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Anti-ROR1 Reference Antibody (zilovertamab vedotin) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-ROR1 Reference Antibody (zilovertamab vedotin)is more than 98.21% ;determined by SEC-HPLC.

Immobilized human ROR1 His at 2 μg/mL can bind Anti-ROR1 Reference Antibody (zilovertamab vedotin);EC50=0.002833μg/mL.

zilovertamab vedotin inhibited the tumor growth of MDA-MB-231on NSG mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 96.6% at 10 mpk.