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Catalog Number | orb1944258 |
---|---|
Category | Small Molecules |
Description | Anti-NASH agent 1 |
CAS Number | 2409685-41-0 |
MW | 423.54 |
Formula | C26H33NO4 |
Biological Activity | Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH). At dosages of 3-10 mg/kg over four weeks, this compound ameliorates hyperlipidemia, liver fat degeneration, and inflammation in a methionine-choline deficiency (MCD)-induced NASH mouse model, exhibiting minimal hepatotoxicity while providing substantial hepatic protection [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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