You have no items in your shopping cart.
Cart summary
Anti-inflammatory agent 54
Catalog Number: orb1944214
| Catalog Number | orb1944214 |
|---|---|
| Category | Small Molecules |
| Description | Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of pro-inflammatory cytokines such as iNOS, TNF-α, IL-6, and IL-1β. It effectively suppresses LPS-induced nitric oxide (NO) production in RAW264.7 macrophages with an IC50 of 2.4 μM and demonstrates in vivo efficacy in a mouse auricular edema model [1]. |
| CAS Number | 2924156-46-5 |
| Purity | 98.00% |
| MW | 328.32 |
| SMILES | C(CNC(/C=C/C1=CC=CO1)=O)N2C=3C(OC2=O)=CC(OC)=CC3 |
| Formula | C17H16N2O5 |
| Biological Activity | Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of pro-inflammatory cytokines such as iNOS, TNF-α, IL-6, and IL-1β. It effectively suppresses LPS-induced nitric oxide (NO) production in RAW264.7 macrophages with an IC50 of 2.4 μM and demonstrates in vivo efficacy in a mouse auricular edema model [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
