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Anti-Hu CD163 Purified
Catalog Number: orb44713
| Catalog Number | orb44713 |
|---|---|
| Category | Antibodies |
| Description | Mouse monoclonal to CD163. CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold. |
| Clonality | Monoclonal |
| Clone Number | GHI/61 |
| Tested applications | FC, IHC-Fr, IP, WB |
| Reactivity | Human |
| Isotype | Mouse IgG1 kappa |
| Immunogen | Hairy cell leukemia cells |
| Concentration | 1 mg/ml |
| Purity | Purified by protein-A affinity chromatography. |
| Conjugation | Unconjugated |
| Target | CD163 |
| Entrez | 9332 |
| UniProt ID | Q86VB7 |
| RRID | AB_10990688 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | anti-Cluster Of Differentiation antibody, anti-CD Read more... |
| Note | For research use only |
| Application notes | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
| Expiration Date | 12 months from date of receipt. |
Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD163 (GHI/61) purified antibody (concentration in sample 2 µg/ml) GAM APC.
Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD163 (GHI/61) purified antibody (concentration in sample 2 µg/ml) GAM APC.
