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Anti-Hu C5aR2 APC
Catalog Number: orb1909789
| Catalog Number | orb1909789 |
|---|---|
| Category | Antibodies |
| Description | C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely. |
| Clonality | Monoclonal |
| Clone Number | 1D9-M12 |
| Tested applications | FC |
| Reactivity | Human, Primate |
| Isotype | Mouse IgG2a kappa |
| Immunogen | L1.2 cells transfected with human C5aR2 |
| Conjugation | APC |
| Target | C5aR2 |
| Entrez | 27202 |
| UniProt ID | Q9P296 |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | C5L2, GPR77, GPF77 Read more... |
| Note | For research use only |
| Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Expiration Date | 12 months from date of receipt. |
Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human C5aR2 (1D9-M12) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human C5aR2 (1D9-M12) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
