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    Annexin A1 Antibody

    Catalog Number: orb640106

    DispatchUsually dispatched within 5-10 working days
    $ 764.00
    Catalog Numberorb640106
    CategoryAntibodies
    DescriptionThe ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
    Species/HostMouse
    ClonalityRecombinant
    Clone NumberANXA1/3869R
    Tested applicationsIHC-P
    ReactivityHuman
    IsotypeRabbit IgG, kappa
    ImmunogenRecombinant human full-length protein was used as the immunogen for the recombinant Annexin A1 antibody.
    Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
    PurityProtein A affinity chromatography
    ConjugationUnconjugated
    Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
    Hazard InformationThis recombinant Annexin A1 antibody is available for research use only.
    UniProt IDP04083
    StorageStore the recombinant Annexin A1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
    Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
    NoteFor research use only
    Application notesOptimal dilution of the antibody should be determined by the researcher.
    Expiration Date12 months from date of receipt.
    Annexin A1 Antibody

    IHC staining of FFPE human tonsil with recombinant Annexin A1 antibody (clone ANXA1/3869R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

    Annexin A1 Antibody

    IHC staining of FFPE human tonsil with recombinant Annexin A1 antibody (clone ANXA1/3869R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

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      FACS,  IF,  IHC-P,  WB

      Human

      Mouse

      Monoclonal

      Unconjugated

      100 μg, 20 μg
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      ELISA,  WB

      Bovine, Canine, Human, Mouse, Porcine, Rat

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      100 μg
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      ELISA,  IF,  IP,  WB

      Human

      Rabbit

      Polyclonal

      Unconjugated

      50 μg, 100 μg
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      ELISA,  WB

      Bovine, Canine

      Human, Mouse, Porcine, Rat

      Goat

      Polyclonal

      Unconjugated

      0.1 mg
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      ICC,  IHC-P,  WB

      Human, Mouse

      Rabbit

      Polyclonal

      Unconjugated

      100 μl
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