Aminopeptidase N Inhibitor

• Catalog Number: orb1693303
• Category: Small Molecules
• Description: Aminopeptidase N Inhibitor
• CAS Number: 596108-59-7
• Purity: 98%
• MW: 370.27
• SMILES: N(=O)(=O)C1=C(OC=2C(C1=O)=CC=CC2CC(O)=O)C3=C(N(=O)=O)C=CC=C3
• Formula: C₁₇H₁₀N₂O₈
• Biological Activity: Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.