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Catalog Number | orb1687195 |
---|---|
Category | Small Molecules |
Description | AMG 837 hemicalcium |
CAS Number | 1291087-14-3 |
Purity | 98% |
MW | 914.954 |
SMILES | CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.[Ca+2] |
Formula | C52H40CaF6O6 |
Biological Activity | AMG 837 hemicalcium is a potent, orally bioavailable and partial agonist of GPR40/FFA1. AMG 837 hemicalcium inhibits specific [ 3 H]AMG 837 binding at the human FFA1 receptor with a pIC 50 of 8.13. AMG 837 hemicalcium could enhance insulin secretion and lower glucose levels in rodents [1] [2] [3]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |