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AMG 837 hemicalcium

AMG 837 hemicalcium

Catalog Number: orb1687195

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Catalog Numberorb1687195
CategorySmall Molecules
DescriptionAMG 837 hemicalcium
CAS Number1291087-14-3
Purity98%
MW914.954
SMILESCC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.[Ca+2]
FormulaC52H40CaF6O6
Biological ActivityAMG 837 hemicalcium is a potent, orally bioavailable and partial agonist of GPR40/FFA1. AMG 837 hemicalcium inhibits specific [ 3 H]AMG 837 binding at the human FFA1 receptor with a pIC 50 of 8.13. AMG 837 hemicalcium could enhance insulin secretion and lower glucose levels in rodents [1] [2] [3].
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.