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Catalog Number | orb1296266 |
---|---|
Category | Small Molecules |
Description | AMG 837 calcium hydrate |
CAS Number | 1259389-38-2 |
Purity | 98.07% |
MW | 950.97 |
SMILES | [H]O[H].[H]O[H].O=C([O-])C[C@H](C#CC)C1=CC=C(OCC2=CC(C3=CC=C(C(F)(F)F)C=C3)=CC=C2)C=C1.O=C([O-])C[C@H](C#CC)C4=CC=C(OCC5=CC(C6=CC=C(C(F)(F)F)C=C6)=CC=C5)C=C4.[Ca+2] |
Formula | C52H48CaF6O8 |
Biological Activity | AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |