AMG-548

• Catalog Number: orb691938
• Category: Small Molecules
• Description: AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and > 5,000-fold selectivity over p38γ and p38δ; shows > 1,000-fold selectivity over other 36 kinases, and is efficacious in acute and chro
• CAS Number: [864249-60-5]
• MW: 461.569
• SMILES: C1=CC=C(C[C@@H](CNC2=NC(C3=CC=NC=C3)=C(C3C=CC4=CC=CC=C4C=3)C(=O)N2C)N)C=C1
• Formula: C₂₉H₂₇N₅O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.