AMG-47a

• Catalog Number: orb1300050
• Category: Small Molecules
• Description: AMG-47a
• CAS Number: 882663-88-9
• Purity: 98%
• MW: 535.56
• SMILES: CC=1C(C2=CC3=C(C=C2)N=C(NCCN4CCOCC4)N=C3)=CC(C(NC5=CC(C(F)(F)F)=CC=C5)=O)=CC1
• Formula: C₂₉H₂₈F₃N₅O₂
• Biological Activity: AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.