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    AM-6494

    AM-6494

    Catalog Number: orb1710454

    DispatchUsually dispatched over 10 weeks
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    Catalog Numberorb1710454
    CategorySmall Molecules
    DescriptionAM-6494
    CAS Number1874232-80-0
    Purity98%
    MW473.5
    SMILESC(OC)[C@]12[C@]([C@](C)(N=C(N)S1)C3=CC(NC(=O)C=4C=NC(OCC#C)=CN4)=CC(F)=C3F)(C2)[H]
    FormulaC22H21F2N5O3S
    Biological ActivityAM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    • AM-6494 [orb1910362]

      [1874232-80-0]

      473.4957

      C22H21F2N5O3S

      1 g, 250 mg, 100 mg
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