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Catalog Number | orb1710454 |
---|---|
Category | Small Molecules |
Description | AM-6494 |
CAS Number | 1874232-80-0 |
Purity | 98% |
MW | 473.5 |
SMILES | C(OC)[C@]12[C@]([C@](C)(N=C(N)S1)C3=CC(NC(=O)C=4C=NC(OCC#C)=CN4)=CC(F)=C3F)(C2)[H] |
Formula | C22H21F2N5O3S |
Biological Activity | AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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