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Catalog Number | orb1305540 |
---|---|
Category | Small Molecules |
Description | Alogliptin Benzoate |
CAS Number | 850649-62-6 |
Purity | 99.95% |
MW | 461.51 |
SMILES | Cn1c(=O)cc(n(c1=O)Cc1ccccc1C#N)N1CCC[C@H](C1)N.c1ccc(cc1)C(=O)O |
Formula | C25H27N5O4 |
Biological Activity | Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may inhibit inflammatory responses by preventing the toll-like receptor 4 (TLR-4)-mediated formation of proinflammatory cytokines. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |