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Catalog Number | orb1685708 |
---|---|
Category | Small Molecules |
Description | AKI603 |
CAS Number | 1432515-73-5 |
Purity | 99.81% |
MW | 409.45 |
SMILES | CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1 |
Formula | C19H23N9O2 |
Biological Activity | AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |