AKI603

• Catalog Number: orb1685708
• Category: Small Molecules
• Description: AKI603
• CAS Number: 1432515-73-5
• Purity: 99.81%
• MW: 409.45
• SMILES: N(C=1N=C(C=C(NC2=NNC(C)=C2)N1)N3CCN(C)CC3)C4=CC=C(N(=O)=O)C=C4
• Formula: C₁₉H₂₃N₉O₂
• Biological Activity: AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.