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AKI603

AKI603

Catalog Number: orb1685708

DispatchUsually dispatched within 3-5 working days
$ 160.00
Catalog Numberorb1685708
CategorySmall Molecules
DescriptionAKI603
CAS Number1432515-73-5
Purity99.81%
MW409.45
SMILESCN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1
FormulaC19H23N9O2
Biological ActivityAKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • AKI603 [orb692001]

    [1432515-73-5]

    409.454

    C19H23N9O2

    100 mg, 250 mg, 1 g