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Catalog Number | orb1689501 |
---|---|
Category | Small Molecules |
Description | Agomelatine hydrochloride |
CAS Number | 1176316-99-6 |
Purity | 100% |
MW | 279.76 |
SMILES | Cl.O=C(NCCC1=CC=CC2=CC=C(OC)C=C21)C |
Formula | C15H18ClNO2 |
Biological Activity | Agomelatine hydrochloride (S-20098 hydrochloride) (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki of 0.1 nM for CHO-hMT1, 0.06 nM for HEK-hMT1, 0.12 nM for CHO-hMT2, and 0.27 nM for HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective antagonist of a 5-HT2C receptor with pKis of 6.4 and 6.2 for native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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