AGI-6780

• Catalog Number: orb181038
• Category: Small Molecules
• Description: AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2-R140Q (IC50=23 nM).
• CAS Number: [1432660-47-3]
• MW: 481.5111
• SMILES: S(C1C([H])=C([H])C(C2=C([H])SC([H])=C2[H])=C(C=1[H])N([H])C(N([H])C1=C([H])C([H])=C([H])C(C(F)(F)F)=C1[H])=O)(N([H])C1([H])C([H])([H])C1([H])[H])(=O)=O
• Formula: C₂₁H₁₈F₃N₃O₃S₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of AGI-6780