AG490

• Catalog Number: orb1713788
• Category: Small Molecules
• Description: JAK-2 kinase inhibitor
• CAS Number: 133550-30-8
• Form/Appearance: Tan solid
• Purity: ≥98% (TLC)
• MW: 294.3
• SMILES: C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
• Formula: C₁₇H₁₄N₂O₃
• Hazard Information: Classification: Acute toxicity, Oral (Category 3), H301 Acute aquatic toxicity (Category 1), H400 Chronic aquatic toxicity (Category 1), H410 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H301 Toxic if swallowed. H410 Very toxic to aquatic life with long lasting effects. Precautionary statements: P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up.
• Solubility (25°C): Soluble in DMSO (30 mg/ml), dimethyl formamide (40 mg/ml) or 100% ethanol (10 mg/ml)
• Source: Synthetic
• Storage: -20°C
• Alternative names: Tyrphostin AG 490, N-Benzyl-3,4-dihydroxybenzylide
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of AG490, a JAK-2 kinase inhibitor. CAS #: 133550-30-8. Molecular Formula: C17H14N2O3. Molecular Weight: 294.3 g/mol.