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Catalog Number | orb1305279 |
---|---|
Category | Small Molecules |
Description | AG490 |
CAS Number | 133550-30-8 |
Purity | 99.70% |
MW | 294.3 |
SMILES | C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2 |
Formula | C17H14N2O3 |
Biological Activity | AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |