AG-7404

• Catalog Number: orb1909149
• Category: Small Molecules
• Description: AG-7404
• CAS Number: 343565-99-1
• MW: 523.54
• SMILES: [C@@H](C(N[C@@H](C[C@H]1C(=O)NCC1)/C=C/C(OCC)=O)=O)(CC#C)N2C(=O)C(NC(=O)C3=NOC(C)=C3)=CC=C2
• Formula: C₂₆H₂₉N₅O₇
• Biological Activity: AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 μM. AG-7404 was fully active against V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 μM, compared to values ranging from 0.202 to 0.407 μM for the V-073-susceptible parental strains.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.