Afatinib (BIBW2992)

Catalog Number: orb154707

Catalog Number	orb154707
Category	Small Molecules
Description	BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
CAS Number	[439081-18-2]
MW	485.9384
SMILES	CN(C)C\C=C\C(=O)NC1=C(OC2COCC2)C=C3C(=C1)C(=NC=N3)NC4C=C(Cl)C(F)=CC=4
Formula	C₂₄H₂₅N₅O₃FCL
Note	For research use only
Expiration Date	12 months from date of receipt.

Chemical structure of Afatinib (BIBW2992)

Item 1 of 1
BIBW2992-MA2 (Afatinib dimaleate) [orb146151]
CAS Number:
[850140-73-7]
MW:
718.09
Formula:
C₃₂H₃₃ClFN₅O₁₁
Sizes Available: 1 g, 100 mg, 250 mg, 1 ml x 10 mm (in DMSO)
Afatinib (BIBW2992) [orb1102123]
Purity:
> 98%
CAS Number:
[439081-18-2]
MW:
485.94
Formula:
C₂₄H₂₅ClFN₅O₃
Sizes Available: 20 mg
BIBW 2992 (Afatinib) [orb340672]
Purity:
> 98%
CAS Number:
850140-72-6
MW:
485.94
Formula:
C₂₄H₂₅ClFN₅O₃
Sizes Available: 50 mg, 10 mg
Afatinib / BIBW2992 [orb762563]
Purity:
> 99%
CAS Number:
439081-18-2
Sizes Available: 20 mg
BIBW2992 (Afatinib) [orb1905282]
CAS Number:
439081-18-2
Sizes Available: 1 ml x 10 mm (in DMSO)