(+/-)- Adomeglivant

• Catalog Number: orb1741009
• Category: Small Molecules
• Description: (+/-)- Adomeglivant
• CAS Number: 872260-47-4
• Purity: 0.98
• MW: 555.63
• SMILES: CC1=C(C(C)=CC(OC(CCC(F)(F)F)C2=CC=C(C(NCCC(O)=O)=O)C=C2)=C1)C3=CC=C(C(C)(C)C)C=C3
• Formula: C₃₂H₃₆F₃NO₄
• Biological Activity: (+/-)- Adomeglivant, also known as LY2409021, is a potent and selective glucagon receptor antagonist. LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes. Blockade of glucagon signalling in patients with type 2 diabetes is well tolerated and results in substantial reduction of fasting and postprandial glucose with minimal hypoglycaemia, but with reversible increases in aminotransferases. Inhibition of glucagon signalling by LY2409021 is a promising potential treatment for patients with type 2 diabetes and should be evaluated in longer clinical trials to better evaluate benefits and risks.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.