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Acivicin hydrochloride
Catalog Number: orb1980253
| Catalog Number | orb1980253 |
|---|---|
| Category | Small Molecules |
| Description | Acivicin hydrochloride is the hydrochloride form of Acivicin (AT125, U42126).Acivicin, a natural product from Streptomyces sviceus (Streptomyces), is a glutamine analog and a potent inhibitor of γ-glutamyltransferase (GGT) and a potent inhibitor of l -Asparagine synthetase and other l-glutamine aminotransferases, and is cytotoxic by blocking nucleotide biosynthesis. |
| CAS Number | 161922-40-3 |
| Purity | 99.14% |
| MW | 215.04 |
| SMILES | [C@H](C(O)=O)(N)[C@]1(ON=C(Cl)C1)[H].Cl |
| Formula | C5H8Cl2N2O3 |
| Biological Activity | Acivicin hydrochloride (AT-125 hydrochloride), derived from Streptomyces sviceus, functions as a γ-glutamyl transpeptidase (GGT) inhibitor. This compound possesses the ability to cross the blood-brain barrier and demonstrates anti-cancer and anti-parasitic properties [1] [2]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
