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Catalog Number | orb1310623 |
---|---|
Category | Small Molecules |
Description | Abexinostat |
CAS Number | 783355-60-2 |
Purity | 98.39% |
MW | 397.42 |
SMILES | C(N(C)C)C=1C=2C(OC1C(NCCOC3=CC=C(C(NO)=O)C=C3)=O)=CC=CC2 |
Formula | C21H23N3O5 |
Biological Activity | PCI-24781 (Abexinostat (PCI24781)) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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