Abemaciclib

• Catalog Number: orb1305567
• Category: Small Molecules
• Description: Abemaciclib
• CAS Number: 1231929-97-7
• Purity: 99.87%
• MW: 506.59
• SMILES: C(C)(C)N1C=2C(=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)N=C1C
• Formula: C₂₇H₃₂F₂N₈
• Biological Activity: Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.